| 摘要 |
The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.
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| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
ALBAUGH, PAMELA ANN;DOMINGUEZ-MANZANARES, ESTEBAN;HONG, JIAN ERIC;HORNBACK, WILLIAM JOSEPH;JIANG, DELU;ORNSTEIN, PAUL LESLIE;THOMPSON, MICHELLE LEE;TROMICZAK, ERIC GEORGE;WU, ZHIPEI;ZARRINMAYEH, HAMIDEH;ZIMMERMAN, DENNIS MICHAEL;CASTANO MANSANET, ANA MARIA;HUFFMAN, LARRY GENE;MILLER, WILLIAM DAVID |
