发明名称 Process for production of 2,3,4-trifluoro-5-(iodo or bromo)-benzoic acid
摘要 The invention provides a process for production of 2,3,4-trifluoro-5-(iodo or bromo)benzoic acid, the process comprising a halogenation step in which direct iodination or bromination of 2,3,4-trifluorobenzoic acid is performed with an iodinating agent or brominating agent in a reaction solvent in the presence of an oxidizing agent. According to the invention, there is provided a process for convenient production of 2,3,4-trifluoro-5-(iodo or bromo)benzoic acid in high yield and high purity in a highly regioselective manner.
申请公布号 US8022247(B2) 申请公布日期 2011.09.20
申请号 US20060887843 申请日期 2006.04.06
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 KOYANO HIROSHI;IIKURA HITOSHI;ISSHIKI YOSHIAKI;KOHCHI YASUNORI
分类号 C07C63/00 主分类号 C07C63/00
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