| 发明名称 |
iRNA Agents Targeting VEGF |
| 摘要 |
The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
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| 申请公布号 |
US2011224282(A1) |
申请公布日期 |
2011.09.15 |
| 申请号 |
US201113043228 |
申请日期 |
2011.03.08 |
| 申请人 |
DE FOUGEROLLES ANTONIN;FRANK-KAMENETSKY MARIA;MANOHARAN MUTHIAH;RAJEEV KALLANTHOTTATHIL G;HADWIGER PHILIPP |
发明人 |
DE FOUGEROLLES ANTONIN;FRANK-KAMENETSKY MARIA;MANOHARAN MUTHIAH;RAJEEV KALLANTHOTTATHIL G.;HADWIGER PHILIPP |
| 分类号 |
A61K31/713;A61K9/00;A61K31/7088;A61K47/02;A61K47/10;A61K47/12;A61K47/48;A61K48/00;A61P27/02;C07H21/02;C12N5/071;C12N5/09 |
主分类号 |
A61K31/713 |
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