发明名称 |
Highly Potent Peptides To Control Cancer And Neurodegenerative Diseases |
摘要 |
This invention provides compositions and method of diminishing or inhibiting autophagy by administering a FLIP protein that binds to Atg3, interfering with the formation of the LC3-Atg4-Atg7-Atg3 conjugation complex necessary for autophagy induction. This invention also provides FLIP peptide fragments that promote or induce autophagy by interfering with the activity of FLIP.
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申请公布号 |
US2011224133(A1) |
申请公布日期 |
2011.09.15 |
申请号 |
US200913055707 |
申请日期 |
2009.07.24 |
申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA |
发明人 |
JUNG JAE U.;LEE JONG-SOO |
分类号 |
A61K38/02;A61K31/7088;A61K38/16;A61K38/17;A61P25/28;A61P31/12;A61P35/00;C07K2/00;C07K7/06;C07K7/08;C07K14/00;C07K16/08;C07K16/18;C12N5/07 |
主分类号 |
A61K38/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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