MANNOSE 6-PHOSPHATE ISOMERASE, MUTANTS THEREOF, AND USE THEREOF

摘要

The present invention relates to a novel mannose 6-phosphate isomerase enzyme, mutants thereof, and a method of manufacturing L-ribose with such mutant enzymes. More particularly, the invention relates to mannose 6-phosphate isomerase enzymes and variants thereof, recombinant expression vectors containing expression genes thereof, microorganisms transformed to express such genes, manufacturing methods for producing large quantities of mannose 6-phosphate isomerase enzyme and its mutants, and production methods for high yields of L-ribose made with the mannose 6-phosphate isomerase mutant enzymes.