发明名称 |
HUMAN MONOCLONAL ANTIBODIES DERIVED FROM HUMAN B CELLS AND HAVING NEUTRALIZING ACTIVITY AGAINST INFLUENZA A VIRUSES |
摘要 |
The present invention relates to human monoclonal antibodies derived from human B cells present in the blood of patients who had recovered from infection with influenza A viruses, wherein the monoclonal antibodies have neutralizing activity against influenza A viruses. The anti-influenza A virus monoclonal antibody of the present invention has binding and neutralizing activities against at least one influenza A virus selected from the group consisting of influenza A virus H1, H2 and H5 subtypes, and thus it is useful for the prevention and treatment of a disease caused by the influenza A virus and is also useful for diagnosis of influenza A virus infection. |
申请公布号 |
CA2849668(A1) |
申请公布日期 |
2011.09.15 |
申请号 |
CA20112849668 |
申请日期 |
2011.03.07 |
申请人 |
CELLTRION, INC. |
发明人 |
SHIN JAE, CHANG;JONG MOOK, KIM;KYE SOOK, YI;HYUN JOO, LEE |
分类号 |
C07K16/10;A61K39/42;A61P31/16;C12N15/13;G01N33/577 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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