发明名称 USE OF 9, 10-ANTHRAQUINONE COMPOUNDS
摘要 Use of 9,10-anthraquinone compounds of formula (I) or pharmaceutical salts thereof or plant extracts containing said compounds in the preparation of anti-HCV medicaments is disclosed, in which Y1 are Y2 are independently hydrogen, hydroxyl or groups of formula (II); and R1, R2, R3, R4, R5 and R6 are independently hydrogen, hydroxyl, carboxyl, cyano group, nitro group, groups of formula (III) or groups selected from those substituted or unsubstituted groups: amino, C1-C6 aliphatic hydrocarbon, C3-C7 cyclic aliphatic hydrocarbon, C1-C6 alkoxy, C2-C7 carbalkoxy, C1-C4 acyloxy, C6-C20 aryl, or 5 to 7 members heterocyclic or benzoheterocyclic thereof; or R5 and R6 form the group of formula (IV). The compounds of present invention are cheap, safe and effective, because that they mostly conic from traditional Chinese medicines and have better anti-HCV effects and lighter side effects.
申请公布号 US2011224414(A1) 申请公布日期 2011.09.15
申请号 US200913130130 申请日期 2009.11.23
申请人 SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY;INSTITUTE PASTEUR OF SHANGHAI, CHINESE ACADEMY OFSCIENCES 发明人 WANG SHUGUANG;ZHONG JIN;KONG DEYUN;HU JUE;LI BO;GAO WEN;GAI CHUNYAN;ZHUANG CHANGIONG;MAO HAITAO
分类号 C07H15/24;C07C49/675;C07C309/44 主分类号 C07H15/24
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