<p>The present invention relates to a method for inhibiting oxidative damage of islet beta cells in vivo in a subject by administering to the subject a therapeutically effective amount of heparan sulfate capable of protecting islet beta cells from reactive oxygen species or in vitro by exposing isolated islet beta cells, prior to transplantation, to a concentration of heparan sulfate that protects them from reactive oxygen species.</p>
申请公布号
WO2011109877(A1)
申请公布日期
2011.09.15
申请号
WO2011AU00284
申请日期
2011.03.11
申请人
THE AUSTRALIAN NATIONAL UNIVERSITY;PARISH, CHRISTOPHER, RICHARD;SIMEONOVIC, CHARMAINE;FREEMAN, CRAIG, GEOFFREY