摘要 |
The present invention relates to an autoantibody specifically recognizing the epitope sequence of FASN (fatty acid synthase), more particularly, to the autoantibody or a fragment comprising an antigen-binding site thereof, a diagnostic composition for hepatocellular carcinoma comprising an agent capable of assessing the expression level of the autoantibody, a hybridoma cell line producing the autoantibody, a diagnostic kit for hepatocellular carcinoma comprising the composition, a method for detecting the autoantibody of hepatocellular carcinoma patient using the composition, and a method for screening a therapeutic agent for hepatocellular carcinoma by administering candidate materials for hepatocellular carcinoma treatment to confirm a reduction in the expression level of autoantibody. |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;CHO, EUN-WIE;HEO, CHANG-KYU;WOO, MI-KYUNG;HWANG, HAI MIN;YOO, HYANG-SOOK;KO, JEONG-HEUN |
发明人 |
CHO, EUN-WIE;HEO, CHANG-KYU;WOO, MI-KYUNG;HWANG, HAI MIN;YOO, HYANG-SOOK;KO, JEONG-HEUN |