PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ALZHEIMER'S DISEASE

摘要

A pharmaceutical composition for treating Alzheimer's disease containing a compound represented by the general formula (I):
wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group;
E is lower alkylene, etc.;
X is S, O, or NR 1 ;
R 1 is a hydrogen atom or lower alkyl;
R 2a , R 2b , R 3a , R 3b , R 4a and R 4b are each independently a hydrogen atom, halogen, hydroxy, etc.;
n and m are each independently an integer of 0 to 3;
n+m is an integer of 1 to 3; and
R 5 is a hydrogen atom, optionally substituted lower alkyl, etc.;
its pharmaceutically acceptable salt, or a solvate thereof as an active ingredient.