| 发明名称 |
RELEASABLE CATIONIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS |
| 摘要 |
<p>The present invention is directed to releasable cationic lipids and nanoparticle compositions for the delivery of nucleic acids and methods of modulating an expression of a target gene using the same. In particular, the invention relates to cationic lipids including an acid labile linker, and nanoparticle compositions containing the same.</p> |
| 申请公布号 |
EP2364085(A1) |
申请公布日期 |
2011.09.14 |
| 申请号 |
EP20090826950 |
申请日期 |
2009.11.17 |
| 申请人 |
ENZON PHARMACEUTICALS, INC. |
发明人 |
ZHAO, HONG;YAN, WEILI;SHI, LIANJUN;ROYZEN, MAKSIM;WU, DECHUN |
| 分类号 |
A01N43/04;C07J41/00;C07J51/00 |
主分类号 |
A01N43/04 |
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