| 发明名称 |
Induction of apoptosis in cancer cells |
| 摘要 |
The present invention provides compounds that are inducers or inhibitors of apoptosis of apoptosis preceded by cell-cycle arrest. In addition, the present invention provides pharmaceutical compositions and methods for treating mammals with leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells.
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| 申请公布号 |
USRE42700(E1) |
申请公布日期 |
2011.09.13 |
| 申请号 |
US20080179865 |
申请日期 |
2008.07.25 |
| 申请人 |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE;OREGON STATE UNIVERSITY;SRI INTERNATIONAL;MOLECULAR MEDICINE RESEARCH INSTITUTE;DEPARTMENT OF VETERANS AFFAIRS;WAYNE STATE UNIVERSITY |
发明人 |
DAWSON MARCIA;FONTANA JOSEPH A.;ZHANG XIAO-KUN;LEID MARK;JONG LING;HOBBS PETER D. |
| 分类号 |
A61K31/54;C07D311/16;A61K31/192;A61K31/352;A61K31/353;A61K31/37;A61K31/404;A61P35/00;A61P35/02;A61P43/00;C07C59/54;C07C59/56;C07C59/72;C07C59/76;C07C65/105;C07C235/08;C07C235/52;C07C255/57;C07C271/02;C07D209/42;C07D311/66;C07D311/74;C07D311/82 |
主分类号 |
A61K31/54 |
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