发明名称 ISOLATION OF A NATURAL LEAD WITH POTENTIAL OF P38 MITOGEN ACTIVATED PROTEIN KINASE AND C-JUN-N TERMINAL KINASE INHIBITING ACTIVITY
摘要 <p>A phytocostituent was isolated from petroleum ether (40-60°C) extract of seeds of Heracleum nepalense and the data obtained from CHN, UV, IR, NMR. Mass spectral data suggests the compound as 9-methoxy-4-(3-methyl-2-oxo-butoxy)-furo[3.2g]chromane-7- one (I). Isolated compound is useful as a lead having p38 MAP Kinase and c-Jun-N-terminal Kinase inhibiting activity and each inhibition is effective in-vivo.</p>
申请公布号 WO2011108000(A1) 申请公布日期 2011.09.09
申请号 WO2010IN00842 申请日期 2010.12.22
申请人 PARNA, CHAKRABORTTY 发明人 PARNA, CHAKRABORTTY
分类号 C07D493/04;A61K31/37;A61P29/00;A61P35/00 主分类号 C07D493/04
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