发明名称 N-9-SUBSTITUTED PURINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE
摘要 The present invention relates to compounds of Formula (I), wherein R1, R2, R3, A1, A2, A3, A4 and D have the meaning described herein. The present invention also relates to pharmaceutical compositions comprising such compounds and therapeutic uses against cancer via inhibition of mTOR and PI3K.
申请公布号 WO2011058027(A3) 申请公布日期 2011.09.09
申请号 WO2010EP67162 申请日期 2010.11.10
申请人 F. HOFFMANN-LA ROCHE AG;LAU, KEVIN, HON LUEN;LEE, WENDY;LYSSIKATOS, JOSEPH, P.;PEI, ZHONGHUA;ROBARGE, KIRK, D. 发明人 LAU, KEVIN, HON LUEN;LEE, WENDY;LYSSIKATOS, JOSEPH, P.;PEI, ZHONGHUA;ROBARGE, KIRK, D.
分类号 A61K31/52;A61P35/00;C07D473/34 主分类号 A61K31/52
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