发明名称 |
SUBSTITUTED AZA-BICYCLIC IMIDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS |
摘要 |
The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold. |
申请公布号 |
CA2791715(A1) |
申请公布日期 |
2011.09.09 |
申请号 |
CA20112791715 |
申请日期 |
2011.03.03 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
PLAYER, MARK R.;CALVO, RAUL;CHEN, JINSHENG;MEEGALLA, SANATH;PARKS, DANIEL;PARSONS, WILLIAM;BALLENTINE, SCOTT;BRANUM, SHAWN |
分类号 |
C07D471/04;A61K31/437;A61K31/4985;A61K31/52;A61P9/00;A61P29/00;C07D473/00;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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