RECOMBINANT CLASSICAL SWINE FEVER VIRUS (CSFV) COMPRISING A MODIFIED E2 PROTEIN AND METHODS FOR GENERATING SAID RECOMBINANT CSFV.

摘要

The invention relates to a recombinant classical swine fever virus (CSFV). A preferred recombinant CSFV comprises a deletion of at least one amino acid in a "TAVSPTTLR" domain of the E2 protein. The invention further relates to a vaccine comprising the recombinant CSFV, a method for generating a recombinant CSFV, and use of a recombinant CSFV.