| 摘要 |
Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, IL6, MMP1, RANTES, MMP9, IL1B, Apolipoprotein A1, Apolipoprotein E, DCN, CILP and COMP. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described. |
| 申请人 |
THE CURATORS OF THE UNIVERSITY OF MISSOURI |
发明人 |
COOK, JAMES L.;COOK, CRISTI R.;STOKER, AARON M.;KUROKI, KELICHI;GARNER, BRIDGET COLLEN;EVANS, RICHARD;ROLLER, BRANDON LEE;JAYA-BALAN, PRAKASH SIDHA |
