| 摘要 |
PROBLEM TO BE SOLVED: To provide a process for producing a recombinant mammalian protein, particularly a recombinant human protein, which can be isolated and purified for therapy. SOLUTION: There provided is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems such as E. coli in comparable circumstances. Processes for improved production of isolated mammalian, particularly human, proteins are provided. COPYRIGHT: (C)2011,JPO&INPIT
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