| 摘要 |
PROBLEM TO BE SOLVED: To provide an intermediate which is useful as a synthetic intermediate of a cholesterol lowering agent (an HMG-CoA reducing enzyme inhibitory drug). SOLUTION: An achiral amine salt of (3R, 5S)-7-substituted-3,5-dihydroxyhept-6-enoic acid represented by general formula (4) (wherein R<SP>1</SP>and R<SP>2</SP>are each a hydrogen atom and R<SP>3</SP>is a 7C-12C aralkyl group, or R<SP>1</SP>is a hydrogen atom and R<SP>2</SP>and R<SP>3</SP>are each a 3C-10C cycloalkyl group) is obtained. COPYRIGHT: (C)2011,JPO&INPIT |
