发明名称 |
FORMULATIONS OF DEOXYCHOLIC ACID AND SALTS THEREOF |
摘要 |
The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5. |
申请公布号 |
US2011218181(A1) |
申请公布日期 |
2011.09.08 |
申请号 |
US20100716070 |
申请日期 |
2010.03.02 |
申请人 |
KYTHERA BIOPHARMACEUTICALS, INC. |
发明人 |
HODGE ROBERT EMIL;WEBSTER JEFFREY DOUGLAS |
分类号 |
A61K31/575;A61P43/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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