| 发明名称 |
NON-ENDOGENOUS, CONSTITUTIVELY ACTIVATED HUMAN G PROTEIN-COUPLED RECEPTOR |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To activate a receptor independently of an endogenous ligand or a compound such as a drug. <P>SOLUTION: A cDNA encodes a mutant human G protein-coupled receptor which is a constitutively activated receptor with a modified amino acid sequence, comprises e.g. hARE-3 (F313K), is non-endogenous, and is constitutively activated. <P>COPYRIGHT: (C)2011,JPO&INPIT |
| 申请公布号 |
JP2011172577(A) |
申请公布日期 |
2011.09.08 |
| 申请号 |
JP20110083188 |
申请日期 |
2011.04.04 |
| 申请人 |
ARENA PHARMACEUTICALS INC |
发明人 |
BEHAN DOMINIC P;LEHMANN-BRUINSMA KARIN;CHALMERS DEREK T;CHEN RUOPING;DANG HUONG T;GORE MARTIN;LIAW CHEN W;LIN I-LIN;LOWITZ KEVIN;WHITE CAROL |
| 分类号 |
C12N15/09;C07K14/705;C12N5/10 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
