发明名称 |
ANTAGONISTS OF IL-6 TO PREVENT OR TREAT CACHEXIA, WEAKNESS, FATIGUE, AND/OR FEVER |
摘要 |
The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level. In another preferred embodiment, the patient's survivability or quality of life will preferably be improved.
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申请公布号 |
US2011217303(A1) |
申请公布日期 |
2011.09.08 |
申请号 |
US201113046860 |
申请日期 |
2011.03.14 |
申请人 |
SMITH JEFFREY T L;SCHATZMAN RANDALL C;LITTON MARK J;LATHAM JOHN |
发明人 |
SMITH JEFFREY T.L.;SCHATZMAN RANDALL C.;LITTON MARK J.;LATHAM JOHN |
分类号 |
A61K39/395;A61P3/00;A61P21/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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