| 摘要 |
A method for the chlorination of a sucrose-6-acylate to produce a 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-beta-acylate wherein said method comprises: (i) reacting the sucrose-6-acylate with a chlorinating agent in a reaction vehicle comprising a tertiary amide in order to chlorinate the 4, V and 6' positions of the sucrose-6-acylate; and (ii) quenching the product stream of (i) to produce a 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-6-acylate; wherein before said quenching, a portion of the tertiary amide is removed. |
