发明名称 |
N-(2,4-dioxo-6-(tetrahydrofuran-2-yl)-7-(trifluoromethyl)-1,4-dihydro-2H-quinazolin-3-yl)methanesulfonamide |
摘要 |
The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
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申请公布号 |
US8012988(B2) |
申请公布日期 |
2011.09.06 |
申请号 |
US20090569402 |
申请日期 |
2009.09.29 |
申请人 |
NOVARTIS AG |
发明人 |
ALLGEIER HANS;AUBERSON YVES;CARCACHE DAVID;FLOERSHEIM PHILIPP;GUIBOURDENCHE CHRISTEL;FROESTL WOLFGANG;KALLEN JOERG;KOLLER MANUEL;MATTES HENRI;NOZULAK JOACHIM;ORAIN DAVID;RENAUD JOHANNE |
分类号 |
A61K31/517;C07C229/56;C07C229/64;C07C229/66;C07C255/18;C07C265/12;C07D207/32;C07D207/337;C07D231/12;C07D237/08;C07D239/26;C07D239/96;C07D241/12;C07D249/06;C07D263/32;C07D307/16;C07D307/54;C07D309/12;C07D401/04;C07D403/04;C07D405/04;C07D413/04 |
主分类号 |
A61K31/517 |
代理机构 |
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地址 |
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