发明名称 |
METHODS, SYSTEMS AND COMPOSITIONS FOR INCREASED MICROORGANISM TOLERANCE TO AND PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP). |
摘要 |
The present invention relates to methods, systems and compositions, including genetically modified microorganisms, adapted to exhibit increased tolerance to 3-hydroxypropionic acid (3-HP), particularly through alterations to interrelated metabolic pathways identified herein as the 3-HP toleragenic pathway complex ("3HPTGC"). In various embodiments these organisms are genetically modified so that an increased 3-HP tolerance is achieved. Also, genetic modifications may be made toprovide at least one genetic modification to any of one or more 3-HP biosynthesis pathways in microorganisms comprising one or more genetic modifications of the 3HPTGC. |
申请公布号 |
MX2011000793(A) |
申请公布日期 |
2011.09.06 |
申请号 |
MX20110000793 |
申请日期 |
2009.07.23 |
申请人 |
OPX BIOTECHNOLOGIES, INC. |
发明人 |
WARNECKE-LIPSCOMB, TANYA;LYNCH, MIKE, D.;GILL, RYAN, T. |
分类号 |
C12N1/21;C12N15/09;C12P7/52 |
主分类号 |
C12N1/21 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|