发明名称 |
Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient |
摘要 |
The present invention relates to a composition for treating atopic dermatitis comprising hirsutenone as an active ingredient. Hirsutenone as the active ingredient of the present composition decreases the number of eosinophil and the level of IgE increased in atopic dermatitis and remarkably reduces expression amounts of immune regulatory cytokine (e.g., IL-4, IL-5 and IL-13) associated with atopic dermatitis. In addition, hirsutenone decreases COX-2 and iNOS expression. Hirsutenone as the active ingredient of the present composition could be effectively used in drugs, cosmetics and foods for treating atopic dermatitis or relieving a symptom of atopic dermatitis.
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申请公布号 |
US8012486(B2) |
申请公布日期 |
2011.09.06 |
申请号 |
US20090454520 |
申请日期 |
2009.05.19 |
申请人 |
CHUNG-ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION |
发明人 |
LEE MIN WON;CHOI YOUNG WOOK;SEO SEONG JUN;LEE DO IK;BANG HYOWEON;LEE CHUNG SOO;LEE JONG CHAN;MYUNG SOON-CHUL;LEE MI-KYUNG;JOO SEONG SOO;CHOI SUN EUN |
分类号 |
A61K39/00;A61K8/02;A61K31/12;A61K47/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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