DIAGNOSITIC METHODS OF TUMOR SUSPECTIBILITY WITH SINGLE NUCLEOTIDE POLYMORPHISMS INSIDE MICRORNA TARGET SITES
摘要
Methods of diagnosing tumor susceptibility or cancer including the step of determining whether a patient has one or more SNP-miRNA expression pattern combinations described herein. Each SNP- miRNA expression pattern combination is supported by data that shows that the SNP is associated with tumor susceptibility because of its ability to affect miRNA binding sites and/or miRNA:mRNA gene regulation.
申请公布号
WO2011106356(A2)
申请公布日期
2011.09.01
申请号
WO2011US25826
申请日期
2011.02.23
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;NICOLOSO, MILENA;CALIN, GEORGE;SUN, HAO;DAVULURI, RAMANA