发明名称 |
SUSTAINED DELIVERY OF THERAPEUTIC AGENTS TO AN EYE COMPARTMENT |
摘要 |
Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing a core; a coating associated with the particle, wherein the wherein the coating is covalently or non-covalently associated with the particle and presents a hydrophilic region to the environment around the particle; and a therapeutic agent are disclosed. The eye compartment can exhibit reduced inflammation or IOP after administration of the drug delivery systems to a patient than if a drug delivery system including an uncoated particle were administered to the patient. |
申请公布号 |
CA2791278(A1) |
申请公布日期 |
2011.09.01 |
申请号 |
CA20112791278 |
申请日期 |
2011.02.25 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
MCDONNELL, PETER J.;KHAN, YASIN A.;LAI, SAMUEL K.;KASHIWABUCHI, RENATA T.;BEHRENS, ASHLEY;HANES, JUSTIN S. |
分类号 |
A61K9/28;A61K31/519;A61K31/52;A61K47/30;A61P27/00;A61P27/02 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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