OPHTHALMIC SOLUTION FOR TREATING OCULAR INFECTION COMPRISING LEVOFLOXACIN OR SALT THEREOF OR SOLVATE OF THE SAME, METHOD FOR TREATING OCULAR INFECTION, LEVOFLOXACIN OR SALT THEREOF OR SOLVATE OF THE SAME, AND USE THEREOF

摘要

Disclosed are a method and dosage of eye drops containing 1.5% (w/v) of levofloxacin, characterized in that, when the eye drops are dropped into the eyes thrice a day, bacterial conjunctivitis can be healed within a short period of time, compared with the conventional case where 0.5% (w/v) eye drops are used thrice a day, without increasing the incidence of side effects. Healing of an eye infection within a short period of time contributes to shortening of the exposure time of a pathogenic bacterium causing the eye infection to levofloxacin. As a result, it is expected that, when used in the aforesaid method and dosage, the levofloxacin-containing eye drops inhibit the appearance of a resistant strain which is caused by the prolonged usage of levofloxacin-containing eye drops in the conventional method or dosage. Moreover, it is confirmed that, when used in the aforesaid method and dosage, the levofloxacin-containing eye drops directly inhibit the appearance of resistance, which is caused by the short-term usage of levofloxacin-containing eye drops in the conventional method or dosage, in pathogenic bacteria causative of eye infections such as Staphylococcus aureus.