The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component. The invention is generally directed to reducing inflammation by administering cells that modulate macrophage activation. The invention is also directed to drug discovery methods to screen for agents that modulate the ability of the cells to modulate macrophage activation. The invention is also directed to cell banks that can be used to provide cells for administration to a subject, the banks comprising cells having desired potency to modulate macrophage activation.
申请公布号
WO2011106521(A1)
申请公布日期
2011.09.01
申请号
WO2011US26067
申请日期
2011.02.24
申请人
ABT HOLDING COMPANY;CASE WESTERN RESERVE UNIVERSITY;TING, ANTHONY, E.;MAYS, ROBERT, W.;HAMILTON, JASON, A.;BUSCH, SARAH, A.;SILVER, JERRY
发明人
TING, ANTHONY, E.;MAYS, ROBERT, W.;HAMILTON, JASON, A.;BUSCH, SARAH, A.;SILVER, JERRY