发明名称 |
ANTI-FLAVIVIRUS THERAPEUTIC |
摘要 |
The present invention relates to anti-flavivirus compounds, including lycorine and derivatives thereof, and their use in treating a subject infected by a flavivirus. The present invention also relates to the use of the anti-flavivirus compounds for the prophylaxis of flavivirus infection. The present invention further relates to a method of suppressing viral RNA synthesis of a flavivirus. Also described is a method of preparing an anti-flavivirus compound for use in the treatment or prophylaxis of flavivirus infection.
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申请公布号 |
US2011212986(A1) |
申请公布日期 |
2011.09.01 |
申请号 |
US200913060035 |
申请日期 |
2009.08.20 |
申请人 |
HEALTH RESEARCH, INC.;REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
SHI PEI-YONG;PUIG-BASAGOITI FRANCESC;PANKIEWICZ KRZYSZTOF W.;FELCZAK KRZYSZTOF;CHEN LIQIANG |
分类号 |
A61K31/475;A61P31/14;C07D491/16;C12N7/00 |
主分类号 |
A61K31/475 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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