FULLY HUMAN ANTI- HER2 MONOCLONAL ANTIBODY, PREPARATION METHOD AND USE THEREOF

摘要

The invention provides a fully humanized anti-HER2 antibody, which has the amino acid sequence of heavy chain variable region as defined in SEQ ID NO : 6 and the amino acid sequence of light chain variable region as defined in SEQ ID NO :8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor.