发明名称 |
FULLY HUMANIZED ANTI-HER2 ANTIBODY, PREPARATION METHOD AND USE THEREOF |
摘要 |
<p>The invention provides a fully humanized anti-HER2 antibody, which has the amino acid sequence of heavy chain variable region as defined in SEQ ID NO : 6 and the amino acid sequence of light chain variable region as defined in SEQ ID NO :8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor.</p> |
申请公布号 |
WO2011103700(A1) |
申请公布日期 |
2011.09.01 |
申请号 |
WO2010CN00511 |
申请日期 |
2010.04.16 |
申请人 |
BIOMAB PHARMACEUTICALS LIMITED;LI, CHUAN;TONG, XIN;KAN, YING |
发明人 |
LI, CHUAN;TONG, XIN;KAN, YING |
分类号 |
C07K16/28;A61P35/00;C12N15/13;C12N15/63 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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