摘要 |
<p>Provided is a cationic polyamino acid useful as a carrier which, together with a nucleic acid, can form a stable complex under physiologic conditions and which can appropriately release the nucleic acid in a cell. The cationic polyamino acid contains both a cationic amino acid residue that has a cationic group in the side chain and a hydrophobic amino acid residue that has a hydrophobic group in the side chain, and has an ability to associate with a nucleic acid. Further, the cationic polyamino acid contains 1 to 20 above-mentioned cationic amino acid residues, and is represented by general formula (1) [wherein each symbol is as defined in the description].</p> |
申请人 |
NANOCARRIER CO., LTD.;THE UNIVERSITY OF TOKYO;KATO, YASUKI;ISHII, ATSUSHI;SHIBATA, NAOYA;HAYASHI, TATSUYUKI;KATAOKA, KAZUNORI;MIYATA, KANJIRO;NISHIYAMA, NOBUHIRO |
发明人 |
KATO, YASUKI;ISHII, ATSUSHI;SHIBATA, NAOYA;HAYASHI, TATSUYUKI;KATAOKA, KAZUNORI;MIYATA, KANJIRO;NISHIYAMA, NOBUHIRO |