发明名称 |
MEGANUCLEASE RECOMBINATION SYSTEM |
摘要 |
The invention relates to a set of genetic constructs which allow the efficient and reproducible introduction of a specific nucleotide sequence at a fixed position in the genome by generating a double strand break at a specific position in the genome using a meganuclease and so stimulating a homologous recombination event at this locus between the genomic site and a transfected donor sequence. The present invention also relates to methods using these constructs and to these materials in the form of a kit. |
申请公布号 |
EP2361308(A1) |
申请公布日期 |
2011.08.31 |
申请号 |
EP20090760591 |
申请日期 |
2009.10.23 |
申请人 |
CELLECTIS |
发明人 |
CABANIOLS, JEAN-PIERRE;CHOULIKA, ANDRE;DELENDA, CHRISTOPHE |
分类号 |
C12N15/85;C12N15/90 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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