<p>The present invention relates to a method for degrading host cell nucleic acids associated with a virus or a viral antigen thereof produced by cell culture, the method comprising at least two steps of nucleic acids degradation with a compound selected from i) an endonuclease and ii) a DNA alkylating agent.</p>
申请公布号
EP2361304(A2)
申请公布日期
2011.08.31
申请号
EP20090745053
申请日期
2009.11.03
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A.
发明人
ANDRE, BRUNO RENE;CHAMPLUVIER, BENOIT PAUL SUZANNE;VAN DER HEYDEN, BENEDICTE