发明名称 |
Immunoglobulin chimeric monomer-dimer hybrids |
摘要 |
The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention. |
申请公布号 |
EP2361932(A1) |
申请公布日期 |
2011.08.31 |
申请号 |
EP20100182890 |
申请日期 |
2004.05.06 |
申请人 |
SYNTONIX PHARMACEUTICALS, INC. |
发明人 |
PETERS, ROBERT T.;MEZO, ADAM R;RIVERA, DANIEL S;BITONTI, ALAN J;STATTEL, JAMES M;LOW, SUSAN C |
分类号 |
C07K14/505;A61K39/395;A61K47/48;C07H21/04;C07K1/02;C07K1/06;C07K1/10;C07K1/107;C07K14/475;C07K14/555;C07K14/56;C07K14/565;C07K14/745;C07K16/00;C07K16/44;C07K16/46;C12N;C12N5/06;C12N9/64;C12N9/96;C12P21/00;C12P21/04 |
主分类号 |
C07K14/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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