发明名称 |
Thermostable nucleic acid polymerase from Thermococcus gorgonarius |
摘要 |
A purified thermostable enzyme is derived form the thermophilic archaebacterium Thermococcus gorgonarius. The enzyme can be native or recombinant, retains approximately 90% of its activity after incubation for two hours at 95° C. in the presence of stabilizing agents and possesses 3′-5′ proofreading exonuclease activity. Thermostable DNA polymerases are useful in many recombinant DNA techniques, especially nucleic acid amplification by the polymerase chain reaction (PCR).
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申请公布号 |
US8008054(B2) |
申请公布日期 |
2011.08.30 |
申请号 |
US20100793602 |
申请日期 |
2010.06.03 |
申请人 |
ROCHE MOLECULAR SYSTEMS, INC. |
发明人 |
ANKENBAUER WALTRAUD;SVETLICHNY VITALY;BONCH-OSMOLOVSKAYA ELIZAVETA;EBENBICHLER CHRISTINE;ANGERER BERNHARD;SCHMITZ-AGHEGUIAN GUDRUN;LAUE FRANK |
分类号 |
C12N9/12;C12N15/09;C12N1/21;C12N15/52;C12N15/70;C12P21/00;C12Q1/68;C12R1/01;C12R1/19 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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地址 |
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