发明名称 |
Modified Cry3A toxins and nucleic acid sequences coding therefor |
摘要 |
Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
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申请公布号 |
US8008248(B2) |
申请公布日期 |
2011.08.30 |
申请号 |
US20090488759 |
申请日期 |
2009.06.22 |
申请人 |
SYNGENTA PARTICIPATIONS AG |
发明人 |
CHEN ERIC;STACY CHERYL M. |
分类号 |
A01H1/00;C07K14/00;A01H5/00;C07K14/325;C12N1/21;C12N5/10;C12N15/09;C12N15/31;C12N15/82;C12P21/02 |
主分类号 |
A01H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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