发明名称 |
Histamine H3 receptor agents, preparation and therapeutic uses |
摘要 |
The present invention discloses novel compounds of Formula I or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases. (Formula I).
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申请公布号 |
US8008296(B2) |
申请公布日期 |
2011.08.30 |
申请号 |
US20060917941 |
申请日期 |
2006.06.28 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
BEAVERS LISA SELSAM;FINLEY DON RICHARD;GADSKI ROBERT ALAN;HIPSKIND PHILIP ARTHUR;HORNBACK WILLIAM JOSEPH;JESUDASON CYNTHIA DARSHINI;PICKARD RICHARD TODD;TAKAKUWA TAKAKO;VAUGHT GRANT MATHEWS |
分类号 |
A61K31/535;A61K31/445;A61K31/497;C07D207/00;C07D409/00;C07D413/00 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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