发明名称 1,2-dihydroquinoline derivative having substituted phenylamino lower alkyl group and ester-introduced phenyl group as substituents
摘要 The compounds represented in general formula (1) and a salt thereof are useful for glucocorticoid receptor modulator. The R1 represents a hydrogen atom or a lower alkyl group; R2 represents a hydrogen atom or a lower alkyl group; R3 and R4 may be the same or different and represents a hydrogen atom or a lower alkyl group; R5 represents a hydrogen atom or a lower alkyl group; R6 represents a halogen atom, a lower alkyl group, a hydroxy group, a lower alkoxy group, a nitro group or a cyano group; X represents —C(O)—, —C(O)NR8—, —S(O)2— and the like; R7 and/or R8 may be the same or different and represent a hydrogen atom, a lower alkyl group which may have a substituent, an aryl group which may have a substituent, a heterocyclic group which may have a substituent, a lower alkoxy group which may have a substituent and the like; Y represents a lower alkylene group; and P represents 0, 1, 2 or 3.
申请公布号 US8008498(B2) 申请公布日期 2011.08.30
申请号 US20070312396 申请日期 2007.11.14
申请人 SANTEN PHARMACEUTICAL CO., LTD. 发明人 MATSUDA MAMORU;NAGATSUKA MASATO;MORI TOSHIYUKI;KOBAYASHI SACHIKO;KATO MASATOMO;TAKAI MIWA
分类号 C07D215/38 主分类号 C07D215/38
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