METHOD OF SIMULATING ACUTE GENERAL PERITONITIS IN RATS

摘要

FIELD: medicine. ^ SUBSTANCE: peritonitis is simulated in rats by peritoneum infection ensured by introduction of bacterial culture E.Coli O-111 dosed 14 bln microbial bodies per 100 g of rat's weights in 2 ml of 20% mannitol to an abdominal cavity through a needle. ^ EFFECT: reliable, approached clinical presentation of a purulent infection in reproducing acute general peritonitis with increasing life expectancy of animals that can be used for developing new methods of treating the disease. ^ 2 ex