发明名称 Anti-neuropilin-1 antibodies for treating angiogenesis
摘要 Provided is an anti-NRP1 antibody capable of inhibiting NRP1's interaction with vascular endothelial cell growth factor (VEGF) comprising a light chain variable domain comprising a specified sequence of CDRL1, CDRL2 and CDRL3. The antibody can be used to inhibit NRP1 mediated angiogenesis in various cancers.
申请公布号 NZ567514(A) 申请公布日期 2011.08.26
申请号 NZ20060567514 申请日期 2006.11.08
申请人 GENENTECH, INC. 发明人 WATTS, RYAN J;WU, YAN
分类号 C07K16/28;A61K39/395 主分类号 C07K16/28
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