发明名称 Methods and formulations for modulating lyn kinase activity and treating related disorders
摘要 Disclosed is a use of a compound, or a pharmaceutically acceptable salt, enantiomer, or diastereomer thereof, in the preparation of a medicament for the treatment or prevention of metabolic syndrome, Syndrome X, obesity, prediabetes, type II diabetes, hypercholesterolemia, hypertension, coronary heart disease; diabetic neuropathy, diabetic retinopathy, erectile dysfunction, kidney disease, and combinations of anyone of more of said disorders in a mammal, wherein said compound has a structure of the formula (I) wherein: R1 is an alkyl group wherein n is an integer from 0 to 5; X is halogen wherein m is 0 or 1; Y is O, S or NH and Z is O or S; and wherein the sum of m plus n is less than or equal to 5.
申请公布号 NZ565955(A) 申请公布日期 2011.08.26
申请号 NZ20060565955 申请日期 2006.08.22
申请人 MELIOR PHARMACEUTICALS I, INC. 发明人 REAUME, ANDREW;SAPORITO, MICHAEL S
分类号 A61K31/495;A61P3/04;C07D247/00 主分类号 A61K31/495
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