COMPOSITIONS AND METHODS FOR THE DETECTION OF ANTIBODIES TO NATIVE HUMAN LEUKOCYTE ANTIGEN

摘要

Provided herein are compositions comprising native and denatured human leukocyte antigens (HLA) and methods of making said compositions. Also provided herein are methods and kits for the detection of antibodies to native HLAs. The native HLAs are by far the primary component of the compositions, which are made by enriching the native HLAs in a mixed composition by means of selective enzymatic reactions.