Fused quinoline derivative and use thereof

摘要

The present invention aims at provision of a quinoline derivative having a neurokinin 2 (NK2) receptor antagonistic action and relates to a compound represented by the formula (I) wherein Ris a hydrogen atom and the like; Ris a hydrogen atom, a hydrocarbon group optionally having substituent(s) and the like; Ris unsubstituted (i.e., absence), a hydrogen atom and the like; Rand Rare the same or different and each is a hydrogen atom, a hydrocarbon group optionally having substituent(s), and the like; Ris (cyclic group optionally having substituent(s)) -carbonyl, and the like; R, R,Rand Rare the same or different and each is a hydrogen atom, halogen and the like; or Rand R,Rand R,and Rand Rmay form a ring together with the adjacent carbon atoms; n is an integer of 1 to 5; --- represents unsubstituted (i.e., absence) or a single bond; and represents a single bond or a double bond, or a salt thereof, and the like.