| 发明名称 |
METHOD FOR STABILIZING ABCA1 ON CELL MEMBRANE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for stabilizing ABCA1 on a cell membrane and a method for screening a substance for stabilizing ABCA1 on a cell membrane. <P>SOLUTION: ABCA1 on a cell membrane is stabilized by inhibiting an interaction between SNX27 and ABCA1. The method for screening a substance for stabilizing ABCA1 on a cell membrane includes using a cell expressing SNX27 and ABCA1 on a cell membrane through inhibition of an interaction between SNX27 and ABCA1. <P>COPYRIGHT: (C)2011,JPO&INPIT |
| 申请公布号 |
JP2011160744(A) |
申请公布日期 |
2011.08.25 |
| 申请号 |
JP20100028493 |
申请日期 |
2010.02.12 |
| 申请人 |
SUGIYAMA YUICHI;HAYASHI KYUIN |
发明人 |
SUGIYAMA YUICHI;HAYASHI KYUIN |
| 分类号 |
C12N15/09;A61K35/12;A61K45/00;A61K48/00;A61P3/06;A61P9/10;C12N5/10;C12N15/113;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
C12N15/09 |
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