摘要 |
This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof. Further this invention relates to a method for the treatment of immune disease or allergy in an animal subject including a mammalian subject, which comprises administering to the animal subject including a mammalian subject a compound of the formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof. |
申请人 |
RAQUALIA PHARMA INC.;KANAZAWA, KIYOSHI;NONOMURA, KAZUHIKO;OKUMURA, TAKAKO;KOIZUMI, SHINICHI |
发明人 |
KANAZAWA, KIYOSHI;NONOMURA, KAZUHIKO;OKUMURA, TAKAKO;KOIZUMI, SHINICHI |