A bifunctional chelating agent of the formula (I): wherein the variables R1, R1 , Q1, Q2 and M are as defined in the description of the present application. Also described is a complex of the above chelating agent to an ion of a stable or radioactive metal; a conjugate of the complex covalently attached to a biological carrier; and a pharmaceutical composition containing the conjugate.
申请公布号
WO2011100829(A1)
申请公布日期
2011.08.25
申请号
WO2011CA00187
申请日期
2011.02.18
申请人
NORDION (CANADA) INC.;ADAM, MIKE;BOROS, ESZTER;FERREIRA, CARA, LEE;ORVIG, CHRIS;PRICE, ERIC, W.
发明人
ADAM, MIKE;BOROS, ESZTER;FERREIRA, CARA, LEE;ORVIG, CHRIS;PRICE, ERIC, W.