发明名称 |
Activation of the Renin-Angiotensin System (RAS) and Sudden Cardiac Death |
摘要 |
Provided herein are methods of treating a medical condition in which RAS activation is increased. The method comprises the step of administering to a subject a c-Src inhibitor in an amount effective to treat the medical condition. The invention also provides a method of treating or preventing a cardiac arrhythmia. The method comprises the step of administering to the subject a c-Src inhibitor in an amount effective to treat or prevent the cardiac arrhythmia. The invention additionally provides a method of delaying the onset of sudden cardiac death. The method comprises the step of administering to the subject a c-Src inhibitor in an amount effective to delay the onset of SCD. Methods of augmenting gap junction function and methods of increasing Connexin 43 levels in a subject in need thereof are further provided. |
申请公布号 |
US2011207741(A1) |
申请公布日期 |
2011.08.25 |
申请号 |
US201113032629 |
申请日期 |
2011.02.22 |
申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
DUDLEY SAMUEL |
分类号 |
A61K31/517;A61K31/4164;A61K31/4375;A61K31/47;A61K31/495;A61K31/496;A61K31/506;A61K31/519;A61K31/52;A61P3/00;A61P3/04;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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